New species of Meromyza from Palaearctic and Oriental China (Diptera: Chloropidae)

Two new Palaearctic species, Meromyza yangi sp. n. and M. zhuae sp. n., and one new Oriental species, M. wuyishanensis sp. n., are described. An updated key to the known species of the genus from China is presented

Review of the genus Meromyza from China (Diptera: Chloropidae)

Areview of the species of the genus Meromyza from China is provided. Two species, Meromyza gansuensis sp. n. and M. ningxiaensis sp. n., are described as new to science. Akey to the species of the genus from China is presented. The distribution of the genus in China is discussed

A review of historical reconstruction methods of land use/land cover

Understanding long-term human-environment interactions requires historical reconstruction of past land-use and land-cover changes. Most reconstructions have been based primarily on consistently available and relatively standardized information from historical sources. Based on available data sources and a retrospective research, in this paper we review the approaches and methods of the digital reconstruction and analyze their advantages and possible constraints in the following aspects: (1) Historical documents contain qualitative or semi-quantitative information about past land use, which also usually include land-cover data, but preparation of archival documents is very time-consuming. (2) Historical maps and pictures offer visual and spatial quantitative land-cover information. (3) Natural archive has significant advantages as a method for reconstructing past vegetation and has its unique possibilities especially when historical records are missing or lacking, but it has great limits of rebuilding certain land-cover types. (4) Historical reconstruction models have been gradually developed from empirical models to mechanistic ones. The method does not only reconstruct the quantity of land use/cover in historical periods, but it also reproduces the spatial distribution. Yet there are still few historical land-cover datasets with high spatial resolution. (5) Reconstruction method based on multiple-source data and multidisciplinary research could build historical land-cover from multiple perspectives, complement the missing data, verify reconstruction results and thus improve reconstruction accuracy. However, there are challenges that make the method still in the exploratory stage. This method can be a long-term development goal for the historical land-cover reconstruction. Researchers should focus on rebuilding historical land-cover dataset with high spatial resolution by developing new models so that the study results could be effectively applied in simulations of climatic and ecological effects

Convolutional Hierarchical Attention Network for Query-Focused Video Summarization

Previous approaches for video summarization mainly concentrate on finding the most diverse and representative visual contents as video summary without considering the user's preference. This paper addresses the task of query-focused video summarization, which takes user's query and a long video as inputs and aims to generate a query-focused video summary. In this paper, we consider the task as a problem of computing similarity between video shots and query. To this end, we propose a method, named Convolutional Hierarchical Attention Network (CHAN), which consists of two parts: feature encoding network and query-relevance computing module. In the encoding network, we employ a convolutional network with local self-attention mechanism and query-aware global attention mechanism to learns visual information of each shot. The encoded features will be sent to query-relevance computing module to generate queryfocused video summary. Extensive experiments on the benchmark dataset demonstrate the competitive performance and show the effectiveness of our approach.Comment: Accepted by AAAI 2020 Conferenc

Advances in immunotyping of colorectal cancer

Immunotherapy has transformed treatment for various types of malignancy. However, the benefit of immunotherapy is limited to a minority of patients with mismatch-repair-deficient (dMMR) and microsatellite instability-high (MSI-H) (dMMR-MSI-H) colorectal cancer (CRC). Understanding the complexity and heterogeneity of the tumor immune microenvironment (TIME) and identifying immune-related CRC subtypes will improve antitumor immunotherapy. Here, we review the current status of immunotherapy and typing schemes for CRC. Immune subtypes have been identified based on TIME and prognostic gene signatures that can both partially explain clinical responses to immune checkpoint inhibitors and the prognosis of patients with CRC. Identifying immune subtypes will improve understanding of complex CRC tumor heterogeneity and refine current immunotherapeutic strategies

Identification of random amplified polymorphic DNA (RAPD) marker of Ph-3 gene for late blight resistance in tomato

Late blight is a highly destructive disease of tomato worldwide. Host resistance is the most effective method for disease control. The application of molecular markers is an efficient way to identify host resistance for breeding programs. In this study, bulked segregant analysis (BSA) was used to search for random amplified polymorphic DNA (RAPD) markers linked to the late blight resistance gene Ph-3, using an F2 population (147 individuals) derived from a cross of tomato lines CLN2037 (resistant) and T2-03 (susceptible). Two hundred and thirty decamer primers with arbitrary sequences were chosen for polymerase chain reaction amplification. One RAPD marker CCPB272-03740 (primer sequence GGTCGATCTG) was found to be tightly linked to the resistance gene Ph-3 and was located 5.8 cm from the resistance gene. Marker CCPB272-03740 is the first marker of gene Ph-3 based on PCR reaction.Key words: Tomato, late blight, random amplified polymorphic DNA (RAPD) marker, gene Ph-3

CYP6AE gene cluster knockout in <i>Helicoverpa armigera</i> reveals role in detoxification of phytochemicals and insecticides

Cotton bollworm is an important agricultural pest with widespread resistance to insecticides. Here Wang et al. identifies CYP6AEs from cotton bollworm involved in detoxifying plant toxins and chemical insecticides through the CRISPR-Cas9-based reverse genetics approach in conjunction with in vitro metabolism